Infarction - tissue death
Myocardium - heart muscle
MI is casued by lack of oxygen to the heart muscle
Ischaemia is the lack of oxygen to the heart muscle
MI occurs when there is cell death
Troponin is a cardiac protein
Cardiac proteins are biomarkers
Changes in cardiac proteins (biomarkers) are indictions of myocardial infarction (MI)
Myocardial infaraction can cause cardiac arrest
Myocardial infaraction can lead to heart failure
Atherosclerosis is the most common cause of myocardial infaraction
Loosened plaques can lead to a blood clot
Atherosclerosis - buildup of cholesterol and fibrous tissue in plaques in the wall of coronary arteries
Macrophages move into arterial walls with inflammation
Foam cells ingest low density lipid proteins
Foams cells die and form a fatty streak
Fatty streak allows blood to clot on it
Fatty streak turns into plaque
Bad blood flow can cause heart cells to die
The dead tissue of the heart will no grow back
A scar made of collagen dies
Cells need oxygen to produce energy
Tissue death and heart scarring alter the conduction pathways of the heart
Troponins are biomarkers
Troponins are measured with a blood test
A rise in troponins occurs within 2-3 hours
Aspirin is given early to reduce the clot size
Aspirin has anti-platelet properties